3 January 2022
Women may derive less benefit from combination immune checkpoint inhibitor (ICI) therapy for advanced melanoma than men, suggest study findings published in JAMA Network Open.
13 December 2021
Altering and reintroducing the haematopoietic stem and progenitor cells (HSPCs) of children with Hurler syndrome results in “extensive” correction of metabolic abnormalities, report researchers.
9 December 2021
Prof. Catherine Lubetzki, winner of the Pasteur-Weizmann/Servier 2021 Prize for her work on myelin regeneration in the treatment of multiple sclerosis
6 December 2021
People with systemic lupus erythematosus (SLE) or scleroderma had a significantly higher risk for all-cause mortality than the general population in 2015–2019, with the greatest excess risk seen in men and younger patients, suggest findings from a large study published in RMD Open.
29 November 2021
Research points to a high prevalence of multifocal disease in children with papillary thyroid carcinoma (PTC), with age and tumour stage possible risk factors for this diagnosis.
Maisie Shindo, from Oregon Health & Science University in Portland, USA, and colleagues report their findings in JAMA Otolaryngology – Head & Neck Surgery from a cohort study of 212 patients aged up to 18 years who underwent thyroidectomy at one of five US hospitals between 2010 and 2020.
19 November 2021
The bile acid transport inhibitor maralixibat, given at a higher dose than previously tested, may significantly improve cholestasis in children with Alagille syndrome, shows the phase 2 ICONIC trial.
