24 January 2022
Suppression of B cells through two different mechanisms of action may warrant further investigation as a treatment strategy for primary Sjögren's syndrome, suggests a phase 2b dose-finding study of the new biologic ianalumab.
17 January 2022
Plasma levels of phosphorylated (p)-tau proteins could serve as a biomarker for cognitive decline in individuals with dementia with Lewy bodies (DLB), say researchers who found an association between increasing levels of the proteins and more rapid decline in Mini-Mental State Examination (MMSE) scores over time.
13 January 2022
Carriage of a specific human leukocyte antigen (HLA) allele is associated with a poor response to immune checkpoint inhibitor (ICI) therapy in patients with a range of tumour types, suggests research published in The Lancet Oncology.
10 January 2022
Researchers identify novel loci that may contribute to the success of asthma treatment in children of African descent, but find these differ between adolescents and younger children.
3 January 2022
Women may derive less benefit from combination immune checkpoint inhibitor (ICI) therapy for advanced melanoma than men, suggest study findings published in JAMA Network Open.
13 December 2021
Altering and reintroducing the haematopoietic stem and progenitor cells (HSPCs) of children with Hurler syndrome results in “extensive” correction of metabolic abnormalities, report researchers.
9 December 2021
Prof. Catherine Lubetzki, winner of the Pasteur-Weizmann/Servier 2021 Prize for her work on myelin regeneration in the treatment of multiple sclerosis
6 December 2021
People with systemic lupus erythematosus (SLE) or scleroderma had a significantly higher risk for all-cause mortality than the general population in 2015–2019, with the greatest excess risk seen in men and younger patients, suggest findings from a large study published in RMD Open.