28 November 2022
The findings of a systematic review and meta-analysis support an association between anxiety and depression symptoms and migraine in children and adolescents.
21 November 2022
The 24-month results from part 2 of the open-label FIREFISH trial suggest that prolonged treatment with risdiplam is associated with continued improvements in motor function and development in infants with type 1 spinal muscular atrophy (SMA).
10 November 2022
Data from a nationwide hospital survey show a marked decrease in the incidence of Kawasaki disease in Japan in 2020 compared with the previous year, with differences in patterns of reduction between children younger than 12 months and those aged 24 months or more.
4 November 2022
Men with systemic sclerosis (SSc)-associated interstitial lung disease (ILD) may have a more severe disease course than women, whereas women with the condition could be more likely to experience certain adverse events (AEs) when treated with immunosuppressive therapy, suggest findings from two studies.
24 October 2022
Data from the open-label extension of the VALOR trial suggest that treatment with the intrathecally administered antisense oligonucleotide tofersen may modify the disease course of amyotrophic lateral sclerosis (ALS) due to SOD1 mutations and lead to improvements in function.
17 October 2022
Phase 1/2 trial findings indicate that autologous chimeric antigen receptor (CAR) T-cell therapy based on the C-type lectin-like molecule-1 (CLL1) may be feasible for children with refractory or relapsed acute myeloid leukaemia (R/R-AML).
10 October 2022
Researchers find that maternal metabolites are associated with distinct foetal growth patterns, elements of which persist until at least 2 years of age.
4 October 2022
People with autoimmune diseases, particularly those with systemic sclerosis (SSc), Addison’s disease or systemic lupus erythematosus (SLE), have a substantially elevated risk of cardiovascular disease (CVD) that should be reflected in their routine care, suggest findings from a large study published in The Lancet.
19 September 2022
Starting young people on closed-loop insulin delivery within 21 days after type 1 diabetes diagnosis does not slow the decline in their beta-cell function over the next 12 months, report the CLOuD investigators.
12 September 2022
FOLFIRINOX (folinic acid, fluorouracil, irinotecan hydrochloride and oxaliplatin) chemotherapy may offer better survival than gemcitabine plus nab-paclitaxel for patients with metastatic pancreatic ductal adenocarcinoma, suggests a comparative effectiveness study published in JAMA Network Open.