L'institut Servier. Supporting research. Fostering vocations

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L‘Institut SERVIER is a non-profit association under French law.
Its aim is to promote all forms of scientific and medical knowledge thus contributing to medical progress,
patient wellbeing and physician expectations.

Les chiffres: 

Colloquia
organized
19

Laureate
Symposium
1

Colloquia
publications edited
230

Grants
allocated
210

Pasteur-Weizmann
Servier
Prize award
5

Latest publications

Neurodegenerative diseases
Delayed lithium treatment positively regulates neurogenesis after radiationinduced damage to the developing brain
Gabriel Lévy
Neurodegenerative diseases

Introduction: Tumors of the central nervous system are the second most frequent tumors in children. Modern therapies have increased greatly the number of cured patients. This leads to new challenges in reducing the therapy-related morbidity. Radiotherapy to the juvenile brain is...

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Oncology
Liver magnetic resonance elastography: reproducibility, predictive factors of failure and new sequences evaluation
Mathilde Wagner
Oncology

Magnetic resonance elastography (MRE) is an imaging technique which assesses the viscoelastic properties of tissues. It is based on the analysis of the tissue’s displacement secondary to a mechanical excitation. It is mainly and daily used for liver fibrosis diagnosis and staging, with excellent...

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Oncology
A new structured helical DPT-peptide containing a short canine adenovirus E4orf4PP2A1, binding sequence inhibits a PI3K survival pathway in radioresistant human glioblastoma cell lines
Frank Ling
Oncology

Background: Glioblastoma is the most common and most aggressive brain cancer in France, with around 2000 cases per year. The radioresistance of glioblastoma cells is a major problem in developing an effective therapy. Previous studies have established that numerous human cancers...

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Scientific Days

2017 Scientific Days Full Program

The Laureate Symposium - November 22nd, 2017

14:45
Post-operative atrial fibrillation, mitochondrial dysfunction and transcriptome
David MONTAIGNE, Salem KACET (+), Dominique LACROIX (Lille), Andrew TINKER (Londres)
15:15
Pathophysiology of the renal artery aneurysms
Bertrand CHAVENT, Jean-Pierre FAVRE (Saint-Etienne), John A. CURCI (Washington)
15:45
Inhaled SERCA2a gene therapy targeting pulmonary hypertension in a pig model
Kiyotake ISHIKAWA representing Nadjib HAMMOUDI (excused), Michel KOMAJDA (Paris), Roger J. HAJJAR (New-York)
16:15
Arterial stiffness in antiphospholipid syndrome patients
Stéphane ZUILY, Denis WAHL (Nancy), Doruk ERKAN (New-York)
16:45
Long-term myocardial and ventricular regional function in patients with Kawasaki disease
Elodie PERDREAU, Jean-Benoît THAMBO (Bordeaux)
17:45
Investigating a novel genetic model of aortic root aneurysm in zebrafish
Maryline ABRIAL (excused), Michel OVIZE (Lyon)
18h15
Effect of mimetic peptide of apolipoprotein A-1 on myocardial function, interstitial fibrosis and ventricular function in a model of metabolic syndrome and diastolic dysfunction in rat
Vincent SPAGNOLI, Alain COHEN-SOLAL (Paris)
18:45
Incremental benefit of cardiac magnetic resonance imaging tissue characterization in profiling cardiac risk of patients presented with suspected myocarditis
Loïc BIERE
19:15
Role of the scaffold protein Angiomotin-like1 in cardiomyocyte proliferation.
Lisa KITASATO, Sigolène MEILHAC (Paris), Minako YAMAOKA-TOJO (Tokyo)
19h45 – 22:00
Dinner-discussion
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2017 Colloquium Program - November 23rd, 2017

Precision medicine and targeted therapies: realities and perspectives.
Organised by :
Bernard DEVULDER, Dominique BELLET et Jean-Paul TILLEMENT
9:00 - 9:20
Introduction - Definitions & Objectives of the colloquium: Selective choices among relevant areas with established therapeutic progress
Pr. Dominique Bellet and Pr. Jean-Paul Tillement
9:20 – 9:50
Integration of individual genetic and kinetic characteristics for the pharmacological optimization of drug use.
Pierre MARQUET (Limoges)
9:50 – 10:20
Genetic susceptibility and aging diseases
Philippe AMOUYEL (Lille)
10:20 – 10:50
Genomic and precision medicine: setting problems and perspectives
Francis GALIBERT (Rennes)
11:20 – 11:50
Managing drug interactions: a clinical decision support system
Jacques TURGEON (Moorestown, New Jersey)
11:50 – 12:20
Therapeutic targeting of Interleukin 17: An example of translational medicine
Pierre MIOSSEC (Lyon)
12:20 – 13:50
Lunch in the reception rooms of 'La Maison de la Chimie'
14:00 – 14:30
Type 2 diabetes and hypercholesterolemia
André SCHEEN (Liège)
14:30 – 15:00
3rd Generation EGRF inhibitors or how to register an anticancer drug in less than 3 years?
Jean-Charles SORIA (Paris)
15:00 – 15:30
Kidney transplantation: an emblematic example of precision medicine to solve an increasingly complex situation
Thierry HAUET (Poitiers)
15:30 – 16:00
Gene, cellular and stem-cell therapies: perspectives and limits
Salima HACEIN-BEY (Paris)
16:00 – 16:30
Precision Medicine: which applications, cost and targeted populations?
Jean-Pierre MICHEL (Genève)
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Download the full program