Actualités

17 janvier 2022

Plasma p-tau levels linked to cognitive decline in people with Lewy body dementia

Plasma levels of phosphorylated (p)-tau proteins could serve as a biomarker for cognitive decline in individuals with dementia with Lewy bodies (DLB), say researchers who found an association between increasing levels of the proteins and more rapid decline in Mini-Mental State Examination (MMSE) scores over time.

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13 janvier 2022

HLA-A*03 alleles linked to poor ICI therapy response

Carriage of a specific human leukocyte antigen (HLA) allele is associated with a poor response to immune checkpoint inhibitor (ICI) therapy in patients with a range of tumour types, suggests research published in The Lancet Oncology.

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10 janvier 2022

Novel loci affect asthma treatment response in children of African descent

Researchers identify novel loci that may contribute to the success of asthma treatment in children of African descent, but find these differ between adolescents and younger children.

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3 janvier 2022

Advanced melanoma nivolumab–ipilimumab outcomes may be poorer in women

Women may derive less benefit from combination immune checkpoint inhibitor (ICI) therapy for advanced melanoma than men, suggest study findings published in JAMA Network Open.

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20 décembre 2021

Médecine du travail et pandémie de Covid-19

Portrait du Dr Jo-Hanna Planchard

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13 décembre 2021

Encouraging interim results for Hurler syndrome gene therapy

Altering and reintroducing the haematopoietic stem and progenitor cells (HSPCs) of children with Hurler syndrome results in “extensive” correction of metabolic abnormalities, report researchers.

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9 décembre 2021

Prix International Pasteur-Weizmann / Servier 2021

Le Pr Catherine Lubetzki, lauréate du Prix Pasteur-Weizmann / Servier 2021 pour ses travaux sur la régénération de la myéline dans le traitement de la sclérose en plaques

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6 décembre 2021

Mortality rates remain elevated in patients with SLE, scleroderma

People with systemic lupus erythematosus (SLE) or scleroderma had a significantly higher risk for all-cause mortality than the general population in 2015–2019, with the greatest excess risk seen in men and younger patients, suggest findings from a large study published in RMD Open.

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3 décembre 2021

Mise en place de la téléconsultation pendant la pandémie de Covid-19

Reportage avec le Dr Bénédicte Mélot

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29 novembre 2021

High prevalence of multifocal disease highlighted for paediatric papillary thyroid carcinoma

Research points to a high prevalence of multifocal disease in children with papillary thyroid carcinoma (PTC), with age and tumour stage possible risk factors for this diagnosis. Maisie Shindo, from Oregon Health & Science University in Portland, USA, and colleagues report their findings in JAMA Otolaryngology – Head & Neck Surgery from a cohort study of 212 patients aged up to 18 years who underwent thyroidectomy at one of five US hospitals between 2010 and 2020.

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