Actualités

A single infusion of allogeneic bone marrow-derived mesenchymal stromal cells (MSCs) was well tolerated and showed preliminary efficacy for severe diffuse systemic sclerosis (SSc) in a phase 1/2 proof-of-concept study by Dominique Farge (Hôpital St-Louis, Paris, France) and colleagues.

The Val66Met polymorphism of the brain-derived neurotrophic factor gene (BDNF) may be “an important moderator” of clinical and tau outcomes in people with dominantly inherited Alzheimer’s disease (DIAD), say researchers.

Findings from The Children’s Oncology Group AAML1331 study suggest that all-trans retinoic acid (ATRA) and arsenic trioxide may be able to reduce or eliminate the need for cytotoxic chemotherapy in children and young adults with a new diagnosis of acute promyelocytic leukaemia (APL).

Introduction of a screening protocol for autism spectrum disorder (ASD) increases the rate of diagnosis, with Spanish-speaking families being the greatest beneficiaries, report researchers.