Actualités

Research points to a high prevalence of multifocal disease in children with papillary thyroid carcinoma (PTC), with age and tumour stage possible risk factors for this diagnosis. Maisie Shindo, from Oregon Health & Science University in Portland, USA, and colleagues report their findings in JAMA Otolaryngology – Head & Neck Surgery from a cohort study of 212 patients aged up to 18 years who underwent thyroidectomy at one of five US hospitals between 2010 and 2020.

The bile acid transport inhibitor maralixibat, given at a higher dose than previously tested, may significantly improve cholestasis in children with Alagille syndrome, shows the phase 2 ICONIC trial.

Plasma glial fibrillary acidic protein (GFAP) outperforms its cerebrospinal fluid (CSF) counterpart in the detection of amyloid-β (Aβ) pathology even in the early stages of Alzheimer’s disease (AD), indicates a cross-sectional study.

Immunological profiles could be used to categorize patients with primary Sjögren’s Syndrome (pSS) or systemic lupus erythematosus (SLE) into distinct subgroups irrespective of diagnosis, suggests UK research published in Arthritis & Rheumatology.