7 février 2022
Risdiplam significantly improves the motor function of patients aged 2–25 years with type 2 or nonambulant type 3 spinal muscular atrophy (SMA) relative to placebo, report the SUNFISH investigators in The Lancet Neurology.
31 janvier 2022
Introduction of a screening protocol for autism spectrum disorder (ASD) increases the rate of diagnosis, with Spanish-speaking families being the greatest beneficiaries, report researchers.
24 janvier 2022
Suppression of B cells through two different mechanisms of action may warrant further investigation as a treatment strategy for primary Sjögren's syndrome, suggests a phase 2b dose-finding study of the new biologic ianalumab.
17 janvier 2022
Plasma levels of phosphorylated (p)-tau proteins could serve as a biomarker for cognitive decline in individuals with dementia with Lewy bodies (DLB), say researchers who found an association between increasing levels of the proteins and more rapid decline in Mini-Mental State Examination (MMSE) scores over time.
13 janvier 2022
Carriage of a specific human leukocyte antigen (HLA) allele is associated with a poor response to immune checkpoint inhibitor (ICI) therapy in patients with a range of tumour types, suggests research published in The Lancet Oncology.
10 janvier 2022
Researchers identify novel loci that may contribute to the success of asthma treatment in children of African descent, but find these differ between adolescents and younger children.
3 janvier 2022
Women may derive less benefit from combination immune checkpoint inhibitor (ICI) therapy for advanced melanoma than men, suggest study findings published in JAMA Network Open.
20 décembre 2021
Portrait du Dr Jo-Hanna Planchard
13 décembre 2021
Altering and reintroducing the haematopoietic stem and progenitor cells (HSPCs) of children with Hurler syndrome results in “extensive” correction of metabolic abnormalities, report researchers.
9 décembre 2021
Le Pr Catherine Lubetzki, lauréate du Prix Pasteur-Weizmann / Servier 2021 pour ses travaux sur la régénération de la myéline dans le traitement de la sclérose en plaques