5 septembre 2022
Two monoclonal antibodies targeting aggregated α-synuclein have failed to improve clinical or imaging measures of Parkinson’s disease progression in the early-stage setting.
29 août 2022
UK researchers have a calculated a “time to cure” of around 6 years after diagnosis for children and young adults with acute lymphoblastic leukaemia (ALL), regardless of risk status.
“Knowing when patients with ALL are cured will allow their timely transfer to clinics devoted to monitoring long-term morbidity rather than relapse and facilitates communication to patients and families”, say Ajay Vora (Great Ormond Street Hospital, London) and colleagues in the Journal of Clinical Oncology.
22 août 2022
A combination of partial deficiencies affecting the C2 and C4A classical complement pathway genes may represent a risk factor for the development of systemic lupus erythematosus (SLE) or primary Sjögren’s syndrome (pSS), shows research from Lars Rönnblom (Uppsala University, Sweden) and team.
27 juillet 2022
Researchers find a high burden of non-specific persistent symptoms in children aged 14 years or younger, with SARS-CoV-2 infection adding to this only slightly.
18 juillet 2022
Adolescent and young adults with rhabdomyosarcoma have more aggressive disease than their paediatric counterparts and might benefit from intensive treatment strategies, suggests an analysis of two European paediatric Soft tissue sarcoma Study Group (EpSSG) trials.
11 juillet 2022
Genetic testing can identify an underlying cause in more than half of complex/syndromic infants with congenital diaphragmatic hernia (CDH), but factors underlying isolated cases remain elusive, say researchers.
4 juillet 2022
Treatment with ultrahigh-dose methylcobalamin may slow the functional decline of amyotrophic lateral sclerosis (ALS) patients with early-stage disease and a moderate progression rate, indicate Japanese trial data published in JAMA Neurology.
27 juin 2022
Children who are diagnosed with type 1 diabetes in early childhood have the most rapid loss of beta cells, research shows.
20 juin 2022
The risk of relapse after treatment for childhood acute lymphoblastic leukaemia (ALL) has decreased in the past 3 decades but the likelihood of successful treatment of relapse has not improved, suggests a review of three Nordic Society of Pediatric Hematology and Oncology (NOPHO) clinical trials.
16 juin 2022
L'Institut Servier, Gustave Roussy et le Dana-Farber Cancer Institute ont signé un accord de coopération pour favoriser les échanges et développer une collaboration bilatérale entre les chercheurs de ces deux centres d’excellence en Oncologie.