TREM2 may have protective effect in Alzheimer’s disease

Researchers have identified an association between faster rates of increase of TREM2 levels in soluble cerebrospinal fluid (CSF) and slower progression of several markers of disease evolution in participants of the Dominantly Inherited Alzheimer Network (DIAN), which they say points to a likely protective effect of TREM2 during the early pathogenesis of Alzheimer’s disease.
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Childhood cancer AEs may be under-reported by clinicians

Children undergoing treatment for cancer report significantly more symptomatic adverse events (AEs) than their clinicians but fewer than their caregivers, suggests research comparing assessments for triads of patients, caregivers and clinicians.
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