Author : Akpéli Nordor
Oncology

Like cancer cells during tumor development, placental cells need to invade their host’s tissues, escape its immune system and access its blood supply system in order to establish pregnancy.

Thus, studying the molecular circuits involved in the development of the placenta might...

Author : Gabriel Lévy
Neurodegenerative diseases

Introduction: Tumors of the central nervous system are the second most frequent tumors in children. Modern therapies have increased greatly the number of cured patients. This leads to new challenges in reducing the therapy-related morbidity. Radiotherapy to the juvenile brain is...

Author : Mathilde Wagner
Oncology

Magnetic resonance elastography (MRE) is an imaging technique which assesses the viscoelastic properties of tissues. It is based on the analysis of the tissue’s displacement secondary to a mechanical excitation. It is mainly and daily used for liver fibrosis diagnosis and staging, with...

Author : Frank Ling
Oncology

Background: Glioblastoma is the most common and most aggressive brain cancer in France, with around 2000 cases per year. The radioresistance of glioblastoma cells is a major problem in developing an effective therapy. Previous studies have established that numerous human cancers...

Author : Benjamin Glenn Chousterman
Immunoinflammatory

Sepsis is a clinical syndrome characterized by intense and dysregulated activation of the immune system during infection. It is a major public health issue with a high prevalence and high mortality. Fil Swirski’s team (Boston, USA) has discovered a new sub-type of B lymphocytes: innate...

Author : Julien Paccou
Diabetes

Purpose: High-resolution peripheral quantitative computed tomography (HR-pQCT) captures novel aspects of bone geometry, volumetric bone mineral density and offers the ability to measure bone microarchitecture, but data relating measures obtained from this technique to diabetic...

Author : Julien Dumurgier
Neurodegenerative diseases

Objective: To investigate the relationship between Alzheimer’s disease (AD) biomarkers and cognitive change in a population of well-functioning elderly people. Methods: We followed up over 3 years 84 participants dementia-free at baseline (mean age: 72.0 years, 59% women...