Authors : Pr Philippe Bousso, Directeur à l'Institut Pasteur de l'Unité ''Dynamique des réponses immunes'', Paris.
Immunology

Interview of Pr Philippe Busso, Director of the dynamic unit of immune responses at the Institut Pasteur, speaker at the mini colloquium "Immunoregulation and cancer".

Authors : Pr Amigorena, Directeur d'Unité immunité et cancer de l'Institut Marie Curie
Immunology

Interview of Pr Amigorena, Director of the Immunity and Cancer Unit of the Marie Curie Institute, speaker at the mini colloquium "Immunoregulation and cancer".

Author : Voir la liste des intervenants dans le programme du Colloque 2018
Immunology

La flore intestinale fait l’objet d’un nombre croissant d’études scientifiques. Et pour cause : la dysbiose serait liée à l’émergence de nombreuses pathologies.

Le microbiote intestinal, c’est tout un monde ! Dans le tube digestif résident...

Authors : Pr Caroline ROBERT, Chef du service de dermatologie à l'Institut Gustave Roussy, Villejuif.
Immunology

Interview of Pr Caroline Robert, Chief of Dermatology at Gustave Roussy Institute, speaker at the mini colloquium "Immunoregulation and cancer".

Authors : Pr. Michel SADELAIN, Memorial Sloane-Kettering Cancer Center, New-York (USA)
Immunology

Interview of Prof. Michel Sadelain, winner of the Pasteur-Weizmann / Servier 2018 Prize.

Prof. Sadelain is the director and founder of the cellular engineering center and head of the gene transfer and genetic expression lab at the Memorial Sloane-Kettering Cancer Center in New York (USA)....

Authors : Bruno Echinard d'après le propos introductif des Professeurs Dominique Bellet (Paris) et Jean-Paul Tillement (Paris), co-présidents du colloque
The patient

The long-held practice of listening to, examining and treating individual patients is converging with genomic, bioinformatic and artificial intelligence technologies to create ‘precision’ medicine, which will transform the way we practise medicine. Learn about how these concepts are...

Authors : Pierre Marquet, Limoges
The patient

Using the example of organ transplantation, P. Marquet describes how translational research may help to optimize therapeutic success, focusing on the genetic determinants of pharmacokinetics and the role of therapeutic drug monitoring.

Authors : Fati Nourhashémi, Toulouse
The patient

Geriatric care will become increasingly important over coming decades as life expectancy increases. F. Nourhashemi describes how the standardized geriatric evaluation is changing to incorporate new understanding of the evolution and impact of frailty and trajectories of disability among elderly...

Authors : Francis Galibert, Rennes
The patient

Mapping of the human genome and the development of next generation sequencing (NGS) have led to advances in screening, pharmacogenetics and targeted therapies. Dr Galibert describes the impact of these advances on precision medicine, and the technological, regulatory, ethical and financial...

Authors : Jacques Turgeon, Montréal
The patient

Advances in bioinformatics have led to sophisticated clinical decision-making tools that can integrate data on a drug’s competitive inhibition, affinity, and metabolic pathways, and on a patient’s environmental and genetic factors. J. Turgeon shows us how these tools help to ensure...

Authors : André J. Scheen, Liège
The patient

Type 2 diabetes and hypercholesterolemia both arise from a combination of genetic predisposition and environmental/lifestyle factors, but treatment practices for these conditions have taken a purely phenotypic approach. Learn how personalised medicine is being applied to treatment decisions in...

Authors : Christophe Le Tourneau, Paris
The patient

Have we reached the stage where each cancer patient should have their tumour sequenced? C. Le Tourneau looks at whether cancer treatment can truly be individualised based on the patient’s tumoral genetic map, or whether we still have some way to go before universal tumour sequencing makes...

Authors : Thierry Hauet, Poitiers
The patient

More and more people are undergoing kidney transplant each year, but the success of these procedures is determined by a range of factors related to the donor, the host and the grafted organ. Although there are several scoring systems available to predict long-term graft outcomes, T. Hauet...

Authors : Salima Hacein-Bey-Abina, Paris
The patient

S. Hacein-Bey describes the history of gene therapy, the triumphs and failures of ex vivo gene transfer technology in hereditary diseases, the development of chimeric antigen receptor (CAR) T cell therapy for cancer, and the exciting opportunities that are emerging with new gene editing...

Authors : Jean-Pierre Michel, Genève
The patient

JP. Michel asks what precision medicine means for clinicians and patients: what is its scope? What are the potential benefits and for whom? But also what are the potential challenges and risks for prescribers, patients, healthcare systems and regulators, and are we ready for the implications of...

Authors : Pr Minako YAMAOKA-TOJO (Tokyo), Pr Denis WAHL (Nancy), Pr Doruk ERKAN (New-York)
Cardiovascular diseases

Symposium of L'Institut Servier Grant Recipients

Author : Pr Salima HACEIN-BEY (Paris)
The patient

17th colloquium: Precision medicine and targeted therapeutics: realities and perspectives

Author : Pr Christophe LE TOURNEAU (Paris)
The patient

17th colloquium: Precision medicine and targeted therapeutics: realities ans perspectives

Author : Pr Fati NOURHASHEMI (Toulouse)
The patient

17th colloquium: Precision medicine and targeted therapeutics: realities ans perspectives

Authors : Dr Bertrand CHAVENT (Saint-Etienne/Saint-Louis - USA), Dr Elodie PERDREAU (Bordeaux/Londres)
Cardiovascular diseases

Symposium of L'Institut Servier Grant Recipients