The study of skin ageing, which is the subject of this L’Institut Servier symposium, falls in line with previous presentations.
Indeed, in 2003 a meeting was dedicated to vulnerability, fragility and ageing; in 2007 another focused on the study of states of functional dependence, and sarcopenia and muscle ageing were proposed in 2012. A continuous increase in life expectancy, which, it must be said, enables the French to live an extra trimester per year, is not just an advantage. Indeed, ensuring healthy ageing with minimal disability, and not just minimizing the resulting economic burden, should be the objective mobilizing the  whole  community,  especially  the  medical  profession  and  policy  makers.  This concept is far from new, as it has already been expressed in the works of Hippocrates!

Improved  living  conditions,  nutrition  and  hygiene  have  contributed  as  much  as  scientific  progress  to  the  dramatic  and  ongoing  results  that  have  pushed  back  the  age of functional dependency. However, the efforts made have not been the same according to the organs considered: if cardiovascular, bronchopulmonary and skeletal ageing, type 2 diabetes and metabolic diseases have attracted considerable interest, the same cannot be said for the study of skin, which more often makes the headlines of women’s magazines than those of medical publications. If  the  myth  of  eternal  youth  has  also  affected  men  since  the  time  of  Dr  Faust,  clinical trials for Brown–Sequard syndrome and the more recent advent of Viagra, the  deification  of  our  solar  star  has  been  highly  controversial.  The  ill-considered  development  of  tanning  booths  justified  a  warning  from  the  National  Academy  of  Medicine because, behind a deceptive mask of apparent good health, sacrificing everything for fashion and aesthetics also runs the undue risk of deadly skin diseases.However, it is enlightening to consider critically, even sardonically, the differences in opinion between dermatologists and rheumatologists. The latter have taught the medical  profession,  following  on  from  paediatricians,  that  vitamin  D  deficiency,  which causes many health disasters affecting not just the bones and joints, cannot be resolved by standard nutrition, while reasonable and sensible sun exposure is effective. Again, a report by the Academy of Medicine reiterated the need for common sense and the limitation of the concept.

This meeting was organized by Camille Francès, who is going to outline the key aspects broadly. The skin, an organ that protects the interior body from the exterior environment, not  only  undergoes  changes  in  appearance  over  the  years,  but  also  altered  functions with an increased risk of cancer. The influence of genetic and external factors such as sun exposure cannot be denied, even if it is known that sun exposure has a beneficial  effect  not  only  on  the  osteoarticular  system  but  also  mental  health.  The  first  part  of  the  day  will  be  dedicated  to  the  influence  of  ageing  on  the  functional  properties  of  the  skin,  dermatoporosis,  healing  abilities  and  carcinogenesis.  The  rapidly developing field of skin pharmacology will then be discussed. The meeting will then consider the possibilities of repair and means of evaluation. Finally, there will be a psychiatrist’s opinion on the myth of eternal youth, largely perpetuated by modern society.

Summary

Introduction : Skin ageing
Pierre Godeau et Camille Francès

The impact of ageing on the functional properties of the skin
Jean-Luc Lévêque

Dermatoporosis
Gürkan Kaya

Carcinogenesis and skin ageing
Nicole Basset-Seguin

The colour of human skin: from research to aesthetics
Thierry Passeron

 Skin healing in the elderly: from pathology to healing and repair
Sylvie Meaume

  Pharmacology and dermatology in ageing
Jean-Hilaire Saurat et Olivier Sorg

Regulatory B cells in autoimmune bullous diseases
Philippe Musette

The value of skin substitutes in the clinical setting and in cosmetology research
Odile Damour, Céline Auxenfans, Eric Dantzer, Christian Echinard,
Amélie Thépot et Morgan Dos Santos

 

The place of cosmetics in skin ageing
Anny Cohen-Letessier

 

Filling techniques: what are the limits?

Annick Pons-Guiraud

The myth of eternal beauty in 2013: the psychiatrist’s perspective

Jean-Paul Mialet

Organizer
Pr Camille Frances
Authors
Pierre Godeau, Camille Francès, Jean-Luc Lévêque, Gürkan Kaya, Nicole Basset-Seguin, Sylvie Meaume, Olivier Sorg, Jean-Hilaire Saurat, Philippe Musette, Yannis Tsouderos, Odile Damour, Céline Auxenfans, Amélie Thépot, Morgan Dos Santos, Eric Dantzer, Christian Echinard, Anny Cohen-Letessier, Annick Pons-Guiraud, Jean-Paul Mialet
Organizer
Pr Camille Frances
Authors
Pierre Godeau, Camille Francès, Jean-Luc Lévêque, Gürkan Kaya, Nicole Basset-Seguin, Sylvie Meaume, Olivier Sorg, Jean-Hilaire Saurat, Philippe Musette, Yannis Tsouderos, Odile Damour, Céline Auxenfans, Amélie Thépot, Morgan Dos Santos, Eric Dantzer, Christian Echinard, Anny Cohen-Letessier, Annick Pons-Guiraud, Jean-Paul Mialet
Category
Ageing
Publication type
Proceedings
Year
2013
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