The microbial community of the human gastrointestinal tract, referred to as the “gut microbiota”, is fundamental to health. The gut microbiota has a major role in digestive physiology and the maintenance of intestinal homeostasis. Dysfunction in the regulation of the intestinal immune response to the microbiota can upset the
fragile balance of this complex ecosystem by modifying its composition, thus creating dysbiosis.
Because it promotes the implantation of bacteria that induce local inflammatory reactions, dysbiosis predisposes the individual to pathological or uncontrolled inflammation. This process is involved in many diseases including chronic Inflammatory Bowel Diseases (IBD) such as Crohn’s disease and ulcerative colitis, two complex diseases that evolve by inflammatory flares alternating with remission phases.

Author
Pr. Harry SOKOL
Author
Pr. Harry SOKOL
Category
Immunology
Publication type
Proceedings
Year
2018
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