Acting on gut microbiota in cardiometabolic disorders: who, what, when and how

CARDIOMETABOLIC NUTRITIONAL DISEASES: AN ALARMING PROBLEM OF PUBLIC HEALTH

According to WHO, the increased prevalence of chronic diseases – or noncommunicable diseases – is closely related to phenomena such as rapid and unplanned urbanization, globalization of unhealthy lifestyles, and aging populations. At the individual level, inadequate diet and sedentariness that result from changes in lifestyle are reflected by an increase in blood pressure, glycemia and lipidemia, which, in connection with the development of obesity, contribute to pathological changes in metabolism that become chronic over time. These combined risk factors are major contributors to the development of cardiovascular diseases, the leading cause of premature death responsible for 17.9 million deaths annually.